Chris Miller, PhD

Associate Professor, Division of Oncology
Washington University School of Medicine

I work in the Division of Oncology at Washington University in St. Louis, where I develop and apply computational tools to give us insight into the origins and progression of cancer.

Tumor evolution through therapy in an Acute Myeloid Leukemia

About me

My work centers on using large-scale genomic data and custom computational methods to understand how cancers arise, how their subclonal populations evolve, and how they respond to therapy, with a particular focus on acute myeloid leukemia.

Core interests:

• Studying the genomic and epigenomic alterations that drive tumorigenesis
• The clonal architecture of tumors and how it evolves in response to therapy
• Multi-omics integration to understand the complex pathways driving cancer
• Effective design and targeting of cancer immunotherapies
• Developing open-source software for integrating, mining, and visualizing genomic data
• Educating the next generation of computationally-savvy scientists

Before moving to WashU, I completed a PhD in Computational Biology at Baylor College of Medicine. My thesis was about using bioinformatic techniques and large-scale data integration to help understand the aetiology of cancer.